WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_STTTCRNTTT_V$IRF_Q6       ID:DB_ID:2426
C=186; O=9; E=0.16; R=56.40; rawP=4.76e-14; adjP=2.19e-12
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000131203 NA IDO1 indoleamine 2,3-dioxygenase 1 3620 ENSG00000131203
2  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
3  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
4  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
5  ENSG00000090554 NA FLT3LG fms-related tyrosine kinase 3 ligand 2323 ENSG00000090554
6  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
7  ENSG00000168062 NA BATF2 basic leucine zipper transcription factor, ATF-like 2 116071 ENSG00000168062
8  ENSG00000179583 NA CIITA class II, major histocompatibility complex, transactivator 4261 ENSG00000179583
9  ENSG00000198133 NA TMEM229B transmembrane protein 229B 161145 ENSG00000198133


Database:Transcription Target       Name:hsa_V$IRF1_01       ID:DB_ID:1880
C=247; O=7; E=0.21; R=33.03; rawP=1.65e-09; adjP=1.90e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
2  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
3  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248
4  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
5  ENSG00000090554 NA FLT3LG fms-related tyrosine kinase 3 ligand 2323 ENSG00000090554
6  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
7  ENSG00000198133 NA TMEM229B transmembrane protein 229B 161145 ENSG00000198133


Database:Transcription Target       Name:hsa_V$IRF2_01       ID:DB_ID:1881
C=125; O=6; E=0.11; R=55.95; rawP=1.13e-09; adjP=1.90e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
2  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
3  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
4  ENSG00000090554 NA FLT3LG fms-related tyrosine kinase 3 ligand 2323 ENSG00000090554
5  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
6  ENSG00000198133 NA TMEM229B transmembrane protein 229B 161145 ENSG00000198133


Database:Transcription Target       Name:hsa_V$IRF_Q6       ID:DB_ID:2256
C=240; O=7; E=0.21; R=34.00; rawP=1.35e-09; adjP=1.90e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
2  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
3  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
4  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
5  ENSG00000168062 NA BATF2 basic leucine zipper transcription factor, ATF-like 2 116071 ENSG00000168062
6  ENSG00000179583 NA CIITA class II, major histocompatibility complex, transactivator 4261 ENSG00000179583
7  ENSG00000198133 NA TMEM229B transmembrane protein 229B 161145 ENSG00000198133


Database:Transcription Target       Name:hsa_V$NFKAPPAB_01       ID:DB_ID:1874
C=250; O=6; E=0.21; R=27.97; rawP=7.15e-08; adjP=6.58e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
2  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
3  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248
4  ENSG00000143153 NA ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 481 ENSG00000143153
5  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347
6  ENSG00000112149 NA CD83 CD83 molecule 9308 ENSG00000112149


Database:Transcription Target       Name:hsa_V$ICSBP_Q6       ID:DB_ID:2210
C=246; O=5; E=0.21; R=23.69; rawP=2.18e-06; adjP=1.43e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000131203 NA IDO1 indoleamine 2,3-dioxygenase 1 3620 ENSG00000131203
2  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
3  ENSG00000204264 NA PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) 5696 ENSG00000204264
4  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
5  ENSG00000168062 NA BATF2 basic leucine zipper transcription factor, ATF-like 2 116071 ENSG00000168062


Database:Transcription Target       Name:hsa_V$ISRE_01       ID:DB_ID:2029
C=246; O=5; E=0.21; R=23.69; rawP=2.18e-06; adjP=1.43e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
2  ENSG00000166710 NA B2M beta-2-microglobulin 567 ENSG00000166710
3  ENSG00000169248 NA CXCL11 chemokine (C-X-C motif) ligand 11 6373 ENSG00000169248
4  ENSG00000204642 NA HLA-F major histocompatibility complex, class I, F 3134 ENSG00000204642
5  ENSG00000168062 NA BATF2 basic leucine zipper transcription factor, ATF-like 2 116071 ENSG00000168062


Database:Transcription Target       Name:hsa_V$IRF7_01       ID:DB_ID:2110
C=250; O=4; E=0.21; R=18.65; rawP=6.26e-05; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
2  ENSG00000240065 NA PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 5698 ENSG00000240065
3  ENSG00000168062 NA BATF2 basic leucine zipper transcription factor, ATF-like 2 116071 ENSG00000168062
4  ENSG00000198133 NA TMEM229B transmembrane protein 229B 161145 ENSG00000198133


Database:Transcription Target       Name:hsa_V$NFKB_Q6       ID:DB_ID:1984
C=254; O=4; E=0.22; R=18.36; rawP=6.66e-05; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138755 NA CXCL9 chemokine (C-X-C motif) ligand 9 4283 ENSG00000138755
2  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
3  ENSG00000143153 NA ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 481 ENSG00000143153
4  ENSG00000112149 NA CD83 CD83 molecule 9308 ENSG00000112149


Database:Transcription Target       Name:hsa_V$NFKB_C       ID:DB_ID:1992
C=262; O=3; E=0.22; R=13.35; rawP=0.0015; adjP=0.0046
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169245 NA CXCL10 chemokine (C-X-C motif) ligand 10 3627 ENSG00000169245
2  ENSG00000019582 NA CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 972 ENSG00000019582
3  ENSG00000125347 NA IRF1 interferon regulatory factor 1 3659 ENSG00000125347




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).